Those are interesting possibilities. It's hard to know what Sutcliff might have done with them, without a military aspect to drive the plot. I expect a story about a woman professional would be more complicated than the two existing novels focused on medicine or the arts, Witch's Brat and Brother Dusty-Feet. (Re: men, can confirm that her Battle of Flodden story has a familiar setup.) But I'm sure someone out there has done Renaissance career women to effect.

I'd love to have something to rec you that fit the bill, but I don't. Have you read The Perilous Gard? Dorothy Dunnett? The Roaring Girl?